Synthesis of novel diary I heterocycle derivatives and their evaluation as growth inhibitory agents and phosphodiesterase 3 inhibitors / Shaimaa Awadain Elsharif ; Supervised Ashraf H. Abadi
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TextLanguage: English Publication details: Cairo : Shaimaa Awadain Elsharif , 2010Description: 90Leaves : charts , facsimiles ; 30cmOther title: - تشييد مشتقات جديدة لثنائى ارايل غير متجانس الحلقة وتقيم قدرتهم كمثبطات النمو ومنع نشاط الفوسفوداى استراز 3 [Added title page title]
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Thesis
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2010.Sh.S (Browse shelf(Opens below)) | Not for loan | 01010110060278000 |
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical chemistry
Milrinone is a cyanopyridone derivative that has been introduced for the treatment of CHF . Its mechanism of action involves inhibition of PDE3 leading to elevation of cAMP increasing the entry of Ca⁺⁺ ions into the cardiac tissues and hence increasing the contractility of the cardiac muscle
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