Design , synthesis of symmetric molecules as potential anti-HCV agents / Alaa Rizk Sanad Ibrahim Leila ; Supervised Ashraf H. Abadi , Mohammad Abdelhalim
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TextLanguage: English Publication details: Cairo : Alaa Rizk Sanad Ibrahim Leila , 2017Description: 101 Leaves : charts , facsimiles ; 30cmOther title: - تصميم وتحضير الجزيئات المتماثلة المضادة لفيروس سي [Added title page title]
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Thesis
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2017.Al.D (Browse shelf(Opens below)) | Not for loan | 01010110075381000 |
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
Until recently, the standard therapy for HCV treatment has been a combination of interferon Ü (IFNÜ) and ribavirin (RBV) which has severe side effects and contraindications. Cure rates reported for this combination therapy were about 50%¹{u⁰⁶⁶B}² therefore, direct-acting antivirals (DAAs) were developed to target viral proteins that are crucial for the HCV lifecycle
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