Thesis (M.Sc)-Cairo University, 2024.

Bibliography: pages 75-87.

Background: Dentin hypersensitivity (DH) is a common and painful dental issue
characterized by brief, sharp pain when exposed dentin reacts to various stimuli.
Bioactive glass and different types of lasers have been tested in treating DH. Yet, none
have incorporated them together in occluding exposed dentinal tubules.
Aim of the study: The current study aimed to evaluate the effect of erbium,
chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser (λ = 2780 nm) and
bioactive glass nanoparticles (NanoBG) paste either alone or in combination with
different sequences on dentinal tubules closure.
Materials and methods: Forty extracted human sound premolars teeth were used for
this study. They were distributed equally into 5 groups (n=10). Control group:
received no treatment. NanoBG Group: treated with nanoBG paste only;
Er,Cr:YSGG laser Group: treated with laser irradiation alone, Er,Cr:YSGG laser +
NanoBG group: treated with nanoBG paste after laser irradiation. NanoBG+
Er,Cr:YSGG laser group: treated with nanoBG paste before laser irradiation. Dentin
specimens were assessed morphologically by scanning electron microscope (SEM),
with subsequent analysis of the mean diameter of dentinal tubules, and calcium and
phosphorous analysis by Energy dispersive x-ray spectroscopy (EDX) analysis.
Results: NanoBG+ Er,Cr:YSGG laser group showed significantly improved dentinal
tubules closure compared to the other groups through SEM imaging. The results were
confirmed by the EDX analysis which revealed the highest calcium and phosphorus
weight %, in addition to recording the lowest mean diameter of dentinal tubules with
statistically significant difference between groups (p<0.05).


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Conclusion: The application of nanoBG and Er,Cr:YSGG laser, and the combination
of both provided satisfactory occlusion of the dentinal tubules. Yet, the combination of
nano-BG and Er,Cr:YSGG laser was found more efficient with superior results, rather
than using each modality alone.

تم استخدام الجسيمات النانوية للزجاج النشط بيولوجيًا و Cr: YSGG laser:Er والمزيج من كلاهماادى الى إغلاقًا مرضيًا لأنابيب العاج. ومع ذلك، تم اكتشاف ان دمج Er:Cr:YSGG laser و الجسيمات النانوية للزجاج النشط بيولوجيًا معأ ادى الى أكثر كفاءة مع نتائج فائقة، بدلاً من استخدام كل طريقة وحدها

Issues also as CD.

Text in English and abstract in Arabic & English.