Design , synthesis and biological evaluation of novel tamoxifen analogues / Mirna Victor Azmy Ayad ; Supervised Ashraf H. Abadi , Nermin Salah Ahmed

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Mirna Victor Azmy Ayad

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TextLanguage: English Publication details: Cairo : Mirna Victor Azmy Ayad , 2017Description: 94 Leaves : charts , facsimiles ; 30cmOther title:

تصميم وتشييد وتقييم بيولوجي لمشتقات تاموكسيفين جديدة [Added title page title]

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Dissertation note: Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry Summary: Tamoxifen is the first SERM discovered to treat metastatic breasr cancer. Tamoxifen is metabolized to give 4-hydroxytamoxifen and 4-hydroxy N-desmethy1 Tamoxifen (Endoxifen) giving higher binding to Estrogen Receptor (ER) and higher potency in berast cancer calls. CYP2D6 and CYP3A4 are responsible for metabolizing Tamoxifen

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Item type	Current library	Home library	Call number	Status	Barcode
Thesis	قاعة الثقاقات الاجنبية - الدور الثالث	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.34.M.Sc.2017.Mi.D (Browse shelf(Opens below))	Not for loan	01010110075332000

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Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

Tamoxifen is the first SERM discovered to treat metastatic breasr cancer. Tamoxifen is metabolized to give 4-hydroxytamoxifen and 4-hydroxy N-desmethy1 Tamoxifen (Endoxifen) giving higher binding to Estrogen Receptor (ER) and higher potency in berast cancer calls. CYP2D6 and CYP3A4 are responsible for metabolizing Tamoxifen

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